{"id":4624,"date":"2013-09-10T19:24:49","date_gmt":"2013-09-10T23:24:49","guid":{"rendered":"http:\/\/68.183.58.104\/learn\/?p=4624"},"modified":"2021-07-14T11:30:04","modified_gmt":"2021-07-14T15:30:04","slug":"new-study-finds-alpha-lipoic-acid-and-inositol-effective-for-metabolic-syndrome-in-postmenopausal-women","status":"publish","type":"post","link":"https:\/\/peachvitamins.com\/learn\/new-study-finds-alpha-lipoic-acid-and-inositol-effective-for-metabolic-syndrome-in-postmenopausal-women\/","title":{"rendered":"New study finds alpha lipoic acid and inositol effective for metabolic syndrome in postmenopausal women"},"content":{"rendered":"<p>The August 2013 issue of the journal <a href=\"http:\/\/www.trialsjournal.com\/content\/14\/1\/273\" target=\"_blank\" rel=\"noopener noreferrer\">Trials <\/a>reported the outcome of a study conducted by researchers in Naples, Italy, which found a benefit for supplementing with alpha lipoic acid and inositol among women with <a href=\"http:\/\/www.nhlbi.nih.gov\/health\/health-topics\/topics\/ms\/\" target=\"_blank\" rel=\"noopener noreferrer\">metabolic syndrome:<\/a> a cluster of symptoms that increase the risk of cardiovascular disease and diabetes. The trial included 155 postmenopausal women who had three or more of five <strong>metabolic syndrome <\/strong>components, and who were at increased risk of breast cancer as determined by family history or history of borderline lesions. (Postmenopausal women with <em>metabolic syndrome<\/em> are at greater risk of breast cancer than the rest of the female population.) Participants were instructed to consume a low-calorie diet and were randomized to receive alpha lipoic acid and inositol, or a placebo for six months.<\/p>\n<p>While the low calorie diet slightly improved <a href=\"https:\/\/web.archive.org\/web\/20150513011234\/http:\/\/diabetes.niddk.nih.gov:80\/DM\/pubs\/insulinresistance\/\" target=\"_blank\" rel=\"noopener noreferrer\">insulin<\/a> levels and <a href=\"https:\/\/web.archive.org\/web\/20150513011234\/http:\/\/diabetes.niddk.nih.gov:80\/DM\/pubs\/insulinresistance\/\" target=\"_blank\" rel=\"noopener noreferrer\">insulin resistance <\/a>in the placebo group, a significant decrease in insulin occurred among 89.3% of women who received alpha lipoic acid and inositol and a reduction in insulin resistance was observed in 66.7% in comparison with values determined at the beginning of the study. A greater percentage of women who received the supplements experienced reductions in triglycerides and a significant increase in high density lipoprotein (HDL), as well as a reduction in waist circumference and waist-hip ratio<\/p>\n<p>\u201cInositol combined with alpha lipoic acid can be used as a dietary supplement in insulin-resistant patients in order to increase their insulin sensitiveness,\u201d authors Immacolata Capasso and colleagues conclude. \u201cDaily consumption of inositol combined with alpha lipoic acid has a significant bearing on metabolic syndrome. As metabolic syndrome is considered a modifiable risk factor of breast tumorigenesis, further studies are required to assess whether inositol combined with alpha lipoic acid can be administered as a dietary supplement in breast cancer primary prevention.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The August 2013 issue of the journal Trials reported the outcome of a study conducted by researchers in Naples, Italy, which found a benefit for supplementing with alpha lipoic acid and inositol among women with metabolic syndrome: a cluster of symptoms that increase the risk of cardiovascular disease and diabetes. The trial included 155 postmenopausal &hellip; <a href=\"https:\/\/peachvitamins.com\/learn\/new-study-finds-alpha-lipoic-acid-and-inositol-effective-for-metabolic-syndrome-in-postmenopausal-women\/\">Continued<\/a><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1274],"tags":[184,182,180,183,181],"acf":[],"_links":{"self":[{"href":"https:\/\/peachvitamins.com\/learn\/wp-json\/wp\/v2\/posts\/4624"}],"collection":[{"href":"https:\/\/peachvitamins.com\/learn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/peachvitamins.com\/learn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/peachvitamins.com\/learn\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/peachvitamins.com\/learn\/wp-json\/wp\/v2\/comments?post=4624"}],"version-history":[{"count":0,"href":"https:\/\/peachvitamins.com\/learn\/wp-json\/wp\/v2\/posts\/4624\/revisions"}],"wp:attachment":[{"href":"https:\/\/peachvitamins.com\/learn\/wp-json\/wp\/v2\/media?parent=4624"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/peachvitamins.com\/learn\/wp-json\/wp\/v2\/categories?post=4624"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/peachvitamins.com\/learn\/wp-json\/wp\/v2\/tags?post=4624"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}